Long Answer
Medium difficulty • Structured explanation
Question 1
Long FormDescribe the structure of a skeletal muscle, starting from the whole muscle down to the level of the myofibril. Include all key structural components.
- Each skeletal muscle is made of muscle bundles called fascicles, held together by a collagenous connective tissue layer called fascia.
- Each fascicle contains many muscle fibres (cells), each lined by the plasma membrane called sarcolemma, which encloses the sarcoplasm. The muscle fibre is a syncitium (multinucleate).
- The sarcoplasmic reticulum within each fibre is the storehouse of calcium ions, critical for contraction.
- The sarcoplasm contains numerous parallelly arranged filaments called myofibrils (myofilaments). Each myofibril displays alternating dark A bands (anisotropic, containing myosin) and light I bands (isotropic, containing actin).
- The functional unit between two successive Z lines is the sarcomere. The Z line bisects each I band; the M line holds thick filaments in the middle of the A band; the H zone is the portion of the A band not overlapped by thin filaments at rest.
- Actin filaments are thin and attached to Z lines; myosin filaments are thick and held by the M line. Both proteins are arranged as parallel rod-like structures along the longitudinal axis of the myofibril.