Application Question
Medium difficulty • Concept in a practical situation
Question 1
Applied ConceptA student observes that when she exercises intensely for a prolonged period, her muscles begin to ache and she feels fatigued. With reference to the chapter, explain the biochemical basis of this observation.
- Repeated and prolonged activation of muscles leads to muscle fatigue due to anaerobic breakdown of glycogen stored in muscle fibres.
- This anaerobic process results in the accumulation of lactic acid in the muscle tissue.
- The lactic acid lowers the pH within the muscle, interfering with the contractile mechanism and causing the muscles to ache and lose their ability to contract efficiently.
- If the exercise involved aerobic muscles (red fibres with mitochondria and myoglobin), fatigue would be slower; white fibres, which rely on anaerobic processes, would fatigue faster.